Japanese Knotweed (Polygonum cuspidatum) is a 1:5 botanical extract rich in natural phenols. It may support liver health and immune function. Research has shown it may help address persister forms of Borrelia and Bartonella. LymeCore Botanicals extracts are made using premium lab tested organic or wildcrafted herbs. They are created using precise measurements, monitoring, and testing per GMP standards. These unique high potency formulas are the best and most effective you will find. LymeCore Botanicals uses the highest quality raw materials available.